Defining Differentially Methylated Regions Specific for the Acquisition of Pluripotency and Maintenance in Human Pluripotent Stem Cells via Microarray

BACKGROUND: Epigenetic regulation is critical for the maintenance of human pluripotent stem cells. It has been shown that pluripotent stem cells, such as embryonic stem cells and induced pluripotent stem cells, appear to have a hypermethylated status compared with differentiated cells. However, the...

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Detalhes bibliográficos
Main Authors: He, WenYin, Kang, XiangJin, Du, HongZi, Song, Bing, Lu, ZhenYu, Huang, Yuling, Wang, Ding, Sun, Xiaofang, Yu, Yang, Fan, Yong
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4177110/
https://ncbi.nlm.nih.gov/pubmed/25250679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0108350
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