Defining Differentially Methylated Regions Specific for the Acquisition of Pluripotency and Maintenance in Human Pluripotent Stem Cells via Microarray

BACKGROUND: Epigenetic regulation is critical for the maintenance of human pluripotent stem cells. It has been shown that pluripotent stem cells, such as embryonic stem cells and induced pluripotent stem cells, appear to have a hypermethylated status compared with differentiated cells. However, the...

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Hauptverfasser: He, WenYin, Kang, XiangJin, Du, HongZi, Song, Bing, Lu, ZhenYu, Huang, Yuling, Wang, Ding, Sun, Xiaofang, Yu, Yang, Fan, Yong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4177110/
https://ncbi.nlm.nih.gov/pubmed/25250679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0108350
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