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The role of α-ketoglutarate–dependent proteins in pluripotency acquisition and maintenance
α-Ketoglutarate is an important metabolic intermediate that acts as a cofactor for several chromatin-modifying enzymes, including histone demethylases and the Tet family of enzymes that are involved in DNA demethylation. In this review, we focus on the function and genomic localization of these α-ke...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6462505/ https://ncbi.nlm.nih.gov/pubmed/30181211 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.TM118.000831 |
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