A central-acting connexin inhibitor, INI-0602, prevents high-fat diet-induced feeding pattern disturbances and obesity in mice

A high-fat diet (HFD) causes obesity by promoting excessive energy intake, and simultaneously, by disturbing the timing of energy intake. Restoring the feeding pattern is sufficient to prevent HFD-induced obesity in mice. However, the molecular mechanism(s) underlying HFD-induced feeding pattern dis...

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Veröffentlicht in:Mol Brain
Hauptverfasser: Sasaki, Tsutomu, Numano, Rika, Yokota-Hashimoto, Hiromi, Matsui, Sho, Kimura, Naobumi, Takeuchi, Hideyuki, Kitamura, Tadahiro
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2018
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5968494/
https://ncbi.nlm.nih.gov/pubmed/29793524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-018-0372-9
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