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Deficiency of Gpr1 improves steroid hormone abnormality in hyperandrogenized mice

BACKGROUND: Polycystic ovary syndrome (PCOS) is a complex genetic disease with multifarious phenotypes. Many researches use dehydroepiandrosterone (DHEA) to induce PCOS in pubertal mouse models. The aim of this study was to investigate the role of GPR1 in dehydroepiandrosterone (DHEA)-induced hypera...

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Detalhes bibliográficos
Publicado no:Reprod Biol Endocrinol
Main Authors: Yang, Ya-Li, Sun, Li-Feng, Yu, Yan, Xiao, Tian-Xia, Wang, Bao-Bei, Ren, Pei-Gen, Tang, Hui-Ru, Zhang, Jian V.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5968470/
https://ncbi.nlm.nih.gov/pubmed/29793502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12958-018-0363-9
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