Deficiency of Gpr1 improves steroid hormone abnormality in hyperandrogenized mice

BACKGROUND: Polycystic ovary syndrome (PCOS) is a complex genetic disease with multifarious phenotypes. Many researches use dehydroepiandrosterone (DHEA) to induce PCOS in pubertal mouse models. The aim of this study was to investigate the role of GPR1 in dehydroepiandrosterone (DHEA)-induced hypera...

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Bibliografiske detaljer
Udgivet i:Reprod Biol Endocrinol
Main Authors: Yang, Ya-Li, Sun, Li-Feng, Yu, Yan, Xiao, Tian-Xia, Wang, Bao-Bei, Ren, Pei-Gen, Tang, Hui-Ru, Zhang, Jian V.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2018
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Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5968470/
https://ncbi.nlm.nih.gov/pubmed/29793502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12958-018-0363-9
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