Inhibition of Col6a5 Improve Lipid Metabolism Disorder in Dihydrotestosterone-Induced Hyperandrogenic Mice

Hyperandrogenism is a key pathological feature of polycystic ovarian syndrome (PCOS). Excess androgen can lead to PCOS-like cell hypertrophy in the ovaries and adipose tissue of rodents. Here, we established a dihydrotestosterone (DHT)-induced hyperandrogenic mouse model to analyze the differences i...

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Vydáno v:Front Cell Dev Biol
Hlavní autoři: Sun, Li-Feng, Yang, Ya-Li, Wang, Mei-Yue, Zhao, Hua-Shan, Xiao, Tian-xia, Li, Meng-Xia, Wang, Bao-Bei, Huang, Chen, Ren, Pei-Gen, Zhang, Jian V.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2021
Témata:
Cell and Developmental Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8181728/
https://ncbi.nlm.nih.gov/pubmed/34109177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.669189
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