Kisspeptin deficiency leads to abnormal adrenal glands and excess steroid hormone secretion

Knockout mice for the kisspeptin receptor, Kiss1r (Kiss1r(−/−)) and its ligand kisspeptin, Kiss1 (Kiss1(−/−)) replicate the phenotype of isolated hypogonadotropic hypogonadism (IHH) associated with variants of these genes in humans. A recent report suggests that kisspeptin may be involved in human f...

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Detalhes bibliográficos
Publicado no:Hum Mol Genet
Main Authors: Berthon, Annabel, Settas, Nikolaos, Delaney, Angela, Giannakou, Andreas, Demidowich, Andrew, Faucz, Fabio R, Seminara, Stephanie B, Chen, Margaret E, Stratakis, Constantine A
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
General Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7906779/
https://ncbi.nlm.nih.gov/pubmed/33089319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddaa215
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