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Kisspeptin deficiency leads to abnormal adrenal glands and excess steroid hormone secretion
Knockout mice for the kisspeptin receptor, Kiss1r (Kiss1r(−/−)) and its ligand kisspeptin, Kiss1 (Kiss1(−/−)) replicate the phenotype of isolated hypogonadotropic hypogonadism (IHH) associated with variants of these genes in humans. A recent report suggests that kisspeptin may be involved in human f...
Shranjeno v:
| izdano v: | Hum Mol Genet |
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| Main Authors: | , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Oxford University Press
2020
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7906779/ https://ncbi.nlm.nih.gov/pubmed/33089319 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddaa215 |
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