Pharmacological activation of PPARγ inhibits hypoxia-induced proliferation through a caveolin-1-targeted and -dependent mechanism in PASMCs

Previously, we and others have demonstrated that activation of peroxisome proliferator-activated receptor γ (PPARγ) by specific pharmacological agonists inhibits the pathogenesis of chronic hypoxia-induced pulmonary hypertension (CHPH) by suppressing the proliferation and migration in distal pulmona...

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Detalhes bibliográficos
Publicado no:Am J Physiol Cell Physiol
Main Authors: Yang, Kai, Zhao, Mingming, Huang, Junyi, Zhang, Chenting, Zheng, Qiuyu, Chen, Yuqin, Jiang, Haiyang, Lu, Wenju, Wang, Jian
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5966784/
https://ncbi.nlm.nih.gov/pubmed/29351409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00143.2017
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