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Pharmacoperones as Novel Therapeutics for Diverse Protein Conformational Diseases
After synthesis, proteins are folded into their native conformations aided by molecular chaperones. Dysfunction in folding caused by genetic mutations in numerous genes causes protein conformational diseases. Membrane proteins are more prone to misfolding due to their more intricate folding than sol...
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| Publicado no: | Physiol Rev |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5966717/ https://ncbi.nlm.nih.gov/pubmed/29442594 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physrev.00029.2016 |
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