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Chaperoning G Protein-Coupled Receptors: From Cell Biology to Therapeutics
G protein-coupled receptors (GPCRs) are membrane proteins that traverse the plasma membrane seven times (hence, are also called 7TM receptors). The polytopic structure of GPCRs makes the folding of GPCRs difficult and complex. Indeed, many wild-type GPCRs are not folded optimally, and defects in fol...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Endocrine Society
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4105357/ https://ncbi.nlm.nih.gov/pubmed/24661201 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/er.2013-1121 |
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