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Pharmacoperone Identification for Therapeutic Rescue of Misfolded Mutant Proteins

G protein-coupled receptors (GPCRs), which includes the gonadotropin-releasing hormone (GnRH) receptor (GnRHR), comprises the largest family of validated drug targets – more than half of all approved drugs derive their benefits by selective targeting of GPCRs. Most drugs in this class are either ago...

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Bibliografski detalji
Glavni autori: Conn, P. Michael, Janovick, Jo Ann
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Research Foundation 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3103854/
https://ncbi.nlm.nih.gov/pubmed/21633718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2011.00006
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