Carregant...

Ipsen 5i is a Novel Potent Pharmacoperone for Intracellularly Retained Melanocortin-4 Receptor Mutants

Inactivating mutations of the melanocortin-4 receptor (MC4R) cause early-onset severe obesity in humans. Comprehensive functional studies show that most of the inactivating mutants of the MC4R are retained intracellularly. In the present study, we investigated whether a small molecule inverse agonis...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Tao, Ya-Xiong, Huang, Hui
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4120685/
https://ncbi.nlm.nih.gov/pubmed/25136332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2014.00131
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!