Docetaxel enhances lysosomal function through TFEB activation

Docetaxel is an effective and commonly used chemotherapeutic drug for cancer. Autophagy has been reported to be involved in the anticancer mechanism of docetaxel. However, the effect of docetaxel on lysosomal function remains elusive. In the present study, we first found that docetaxel treatment enh...

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Udgivet i:Cell Death Dis
Main Authors: Zhang, Jianbin, Wang, Jigang, Wong, Yin Kwan, Sun, Xin, Chen, Yun, Wang, Liming, Yang, Liu, Lu, Liqin, Shen, Han-Ming, Huang, Dongsheng
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5966422/
https://ncbi.nlm.nih.gov/pubmed/29795139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0571-4
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