Oblongifolin C suppresses lysosomal function independently of TFEB nuclear translocation

Lysosomes are the terminal organelles of the autophagic-endocytic pathway and play a key role in the degradation of autophagic contents. We previously reported that a natural compound oblongifolin C (OC) increased the number of autophagosomes and impaired the degradation of P62, most likely via supp...

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Detaylı Bibliyografya
Yayımlandı:Acta Pharmacol Sin
Asıl Yazarlar: Wu, Man, Lao, Yuan-zhi, Tan, Hong-sheng, Lu, Guang, Ren, Yi, Zheng, Zhao-qing, Yi, Juan, Fu, Wen-wei, Shen, Han-ming, Xu, Hong-xi
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2018
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6786433/
https://ncbi.nlm.nih.gov/pubmed/30333555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41401-018-0167-7
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