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Proteasome Inhibition Activates Autophagy-Lysosome Pathway Associated With TFEB Dephosphorylation and Nuclear Translocation
Ubiquitin-proteasome pathway (UPS) and autophagy-lysosome pathway (ALP) are the two major protein degradation pathways, which are critical for proteostasis. Growing evidence indicates that proteasome inhibition-induced ALP activation is an adaptive response. Transcription Factor EB (TFEB) is a maste...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | Front Cell Dev Biol |
|---|---|
| Prif Awduron: | , , , , , , , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
Frontiers Media S.A.
2019
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6713995/ https://ncbi.nlm.nih.gov/pubmed/31508418 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2019.00170 |
| Tagiau: |
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