Docetaxel enhances lysosomal function through TFEB activation

Docetaxel is an effective and commonly used chemotherapeutic drug for cancer. Autophagy has been reported to be involved in the anticancer mechanism of docetaxel. However, the effect of docetaxel on lysosomal function remains elusive. In the present study, we first found that docetaxel treatment enh...

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Опубликовано в: :Cell Death Dis
Главные авторы: Zhang, Jianbin, Wang, Jigang, Wong, Yin Kwan, Sun, Xin, Chen, Yun, Wang, Liming, Yang, Liu, Lu, Liqin, Shen, Han-Ming, Huang, Dongsheng
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2018
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5966422/
https://ncbi.nlm.nih.gov/pubmed/29795139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0571-4
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