Docetaxel enhances lysosomal function through TFEB activation

Docetaxel is an effective and commonly used chemotherapeutic drug for cancer. Autophagy has been reported to be involved in the anticancer mechanism of docetaxel. However, the effect of docetaxel on lysosomal function remains elusive. In the present study, we first found that docetaxel treatment enh...

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I publikationen:Cell Death Dis
Huvudupphovsmän: Zhang, Jianbin, Wang, Jigang, Wong, Yin Kwan, Sun, Xin, Chen, Yun, Wang, Liming, Yang, Liu, Lu, Liqin, Shen, Han-Ming, Huang, Dongsheng
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2018
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5966422/
https://ncbi.nlm.nih.gov/pubmed/29795139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0571-4
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