Impact of benznidazole treatment on the functional response of Trypanosoma cruzi antigen-specific CD4(+)CD8(+) T cells in chronic Chagas disease patients

BACKGROUND: Chagas disease is caused by Trypanosoma cruzi. The persistence of the parasite is associated with the disease chronicity and the impairment of the cellular immune response. It has been reported that the CD4(+)CD8(+) T cell population expands in chronic Chagas disease patients. Few studie...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:PLoS Negl Trop Dis
Autori principali: Pérez-Antón, Elena, Egui, Adriana, Thomas, M. Carmen, Puerta, Concepción J., González, John Mario, Cuéllar, Adriana, Segovia, Manuel, López, Manuel Carlos
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2018
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5965897/
https://ncbi.nlm.nih.gov/pubmed/29750791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0006480
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