Impact of benznidazole treatment on the functional response of Trypanosoma cruzi antigen-specific CD4(+)CD8(+) T cells in chronic Chagas disease patients

BACKGROUND: Chagas disease is caused by Trypanosoma cruzi. The persistence of the parasite is associated with the disease chronicity and the impairment of the cellular immune response. It has been reported that the CD4(+)CD8(+) T cell population expands in chronic Chagas disease patients. Few studie...

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Detalhes bibliográficos
Publicado no:PLoS Negl Trop Dis
Main Authors: Pérez-Antón, Elena, Egui, Adriana, Thomas, M. Carmen, Puerta, Concepción J., González, John Mario, Cuéllar, Adriana, Segovia, Manuel, López, Manuel Carlos
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5965897/
https://ncbi.nlm.nih.gov/pubmed/29750791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0006480
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