Impact of benznidazole treatment on the functional response of Trypanosoma cruzi antigen-specific CD4(+)CD8(+) T cells in chronic Chagas disease patients

BACKGROUND: Chagas disease is caused by Trypanosoma cruzi. The persistence of the parasite is associated with the disease chronicity and the impairment of the cellular immune response. It has been reported that the CD4(+)CD8(+) T cell population expands in chronic Chagas disease patients. Few studie...

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Bibliografische gegevens
Gepubliceerd in:PLoS Negl Trop Dis
Hoofdauteurs: Pérez-Antón, Elena, Egui, Adriana, Thomas, M. Carmen, Puerta, Concepción J., González, John Mario, Cuéllar, Adriana, Segovia, Manuel, López, Manuel Carlos
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2018
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5965897/
https://ncbi.nlm.nih.gov/pubmed/29750791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0006480
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