Alterations in the brain interactome of the intrinsically disordered N-terminal domain of the cellular prion protein (PrP(C)) in Alzheimer’s disease

The cellular prion protein (PrP(C)) is implicated in neuroprotective signaling and neurotoxic pathways in both prion diseases and Alzheimer’s disease (AD). Specifically, the intrinsically disordered N-terminal domain (N-PrP) has been shown to interact with neurotoxic ligands, such as Aβ and Scrapie...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Ulbrich, Sarah, Janning, Petra, Seidel, Ralf, Matschke, Jakob, Gonsberg, Anika, Jung, Sebastian, Glatzel, Markus, Engelhard, Martin, Winklhofer, Konstanze F., Tatzelt, Jörg
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2018
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5965872/
https://ncbi.nlm.nih.gov/pubmed/29791485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0197659
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires