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Synthesis of β-nicotinamide riboside using an efficient two-step methodology

A two-step chemical methodology for the synthesis of β-nicotinamide riboside (NR) is described. NR has achieved wide use as an NAD(+) precursor (vitamin B3) and can significantly increase central metabolite NAD(+) concentrations in mammalian cells. β-NR can be prepared with an efficient two-step pro...

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Bibliografiske detaljer
Udgivet i:Curr Protoc Nucleic Acid Chem
Main Authors: Zhang, Ning, Sauve, Anthony A.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5965287/
https://ncbi.nlm.nih.gov/pubmed/29275540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpnc.43
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