Nicotinamide Riboside Kinase Structures Reveal New Pathways to NAD(+)

The eukaryotic nicotinamide riboside kinase (Nrk) pathway, which is induced in response to nerve damage and promotes replicative life span in yeast, converts nicotinamide riboside to nicotinamide adenine dinucleotide (NAD(+)) by phosphorylation and adenylylation. Crystal structures of human Nrk1 bou...

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Detalhes bibliográficos
Main Authors: Tempel, Wolfram, Rabeh, Wael M, Bogan, Katrina L, Belenky, Peter, Wojcik, Marzena, Seidle, Heather F, Nedyalkova, Lyudmila, Yang, Tianle, Sauve, Anthony A, Park, Hee-Won, Brenner, Charles
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2007
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1994991/
https://ncbi.nlm.nih.gov/pubmed/17914902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.0050263
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