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A haunted beast: Targeting STAT5B(N642H) in T-Cell Neoplasia

The somatic hot spot mutation STAT5B(N642H) was found in many T cell leukemia/lymphoma patients. We generated and analyzed a transgenic mouse model with hematopoietic STAT5B(N642H) expression that caused aggressive T-cell leukemia/lymphomas. Herein, we discuss the scientific merit of our model and i...

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Detalhes bibliográficos
Publicado no:Mol Cell Oncol
Main Authors: Pham, Ha Thi Thanh, Hengstschläger, Markus, Moriggl, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5964446/
https://ncbi.nlm.nih.gov/pubmed/29876519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2018.1435181
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