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Human stem cells alter the invasive properties of somatic cells via paracrine activation of mTORC1

Controlled invasion is essential during many physiological processes, whereas its deregulation is a hallmark of cancer. Here we demonstrate that embryonic, induced pluripotent and amniotic fluid stem cells share the property to induce the invasion of primary somatic cells of various origins through...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Rosner, Margit, Pham, Ha Thi Thanh, Moriggl, Richard, Hengstschläger, Markus
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5605703/
https://ncbi.nlm.nih.gov/pubmed/28928383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00661-x
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