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Trimethylsilyl-Protected Alkynes as Selective Cross Coupling Partners in Ti-Catalyzed [2+2+1] Pyrrole Synthesis

Trimethylsilyl (TMS)-protected alkynes serve as selective alkyne cross coupling partners in Ti-catalyzed [2+2+1] pyrrole synthesis. Reactions of TMS-protected alkynes with internal alkynes and azobenzene catalyzed by Ti imido catalysts yield pentasubstituted 2-TMS-pyrroles with greater than 90% sele...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Chiu, Hsin-Chun, Tonks, Ian A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5964026/
https://ncbi.nlm.nih.gov/pubmed/29573100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201800595
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