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CRL7(SMU1) E3 ligase complex-driven H2B ubiquitylation functions in sister chromatid cohesion by regulating SMC1 expression

Cullin–RING-type E3 ligases (CRLs) control a broad range of biological processes by ubiquitylating numerous cellular substrates. However, the role of CRL E3 ligases in chromatid cohesion is unknown. In this study, we identified a new CRL-type E3 ligase (designated as CRL7(SMU1) complex) that has an...

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Dades bibliogràfiques
Publicat a:J Cell Sci
Autors principals: Shah, Varun Jayeshkumar, Maddika, Subbareddy
Format: Artigo
Idioma:Inglês
Publicat: The Company of Biologists Ltd 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5963846/
https://ncbi.nlm.nih.gov/pubmed/29507117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.213868
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