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CRL7(SMU1) E3 ligase complex-driven H2B ubiquitylation functions in sister chromatid cohesion by regulating SMC1 expression

Cullin–RING-type E3 ligases (CRLs) control a broad range of biological processes by ubiquitylating numerous cellular substrates. However, the role of CRL E3 ligases in chromatid cohesion is unknown. In this study, we identified a new CRL-type E3 ligase (designated as CRL7(SMU1) complex) that has an...

詳細記述

保存先:
書誌詳細
出版年:J Cell Sci
主要な著者: Shah, Varun Jayeshkumar, Maddika, Subbareddy
フォーマット: Artigo
言語:Inglês
出版事項: The Company of Biologists Ltd 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5963846/
https://ncbi.nlm.nih.gov/pubmed/29507117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.213868
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