A positively charged channel within the Smc1/Smc3 hinge required for sister chromatid cohesion

Cohesin's structural maintenance of chromosome 1 (Smc1) and Smc3 are rod-shaped proteins with 50-nm long intra-molecular coiled-coil arms with a heterodimerization domain at one end and an ABC-like nucleotide-binding domain (NBD) at the other. Heterodimerization creates V-shaped molecules with...

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Main Authors: Kurze, Alexander, Michie, Katharine A, Dixon, Sarah E, Mishra, Ajay, Itoh, Takehiko, Khalid, Syma, Strmecki, Lana, Shirahige, Katsuhiko, Haering, Christian H, Löwe, Jan, Nasmyth, Kim
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2011
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3025461/
https://ncbi.nlm.nih.gov/pubmed/21139566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.315
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