The Chromosomal Association of the Smc5/6 Complex Depends on Cohesion and Predicts the Level of Sister Chromatid Entanglement

The cohesin complex, which is essential for sister chromatid cohesion and chromosome segregation, also inhibits resolution of sister chromatid intertwinings (SCIs) by the topoisomerase Top2. The cohesin-related Smc5/6 complex (Smc5/6) instead accumulates on chromosomes after Top2 inactivation, known...

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Bibliographic Details
Main Authors: Jeppsson, Kristian, Carlborg, Kristian K., Nakato, Ryuichiro, Berta, Davide G., Lilienthal, Ingrid, Kanno, Takaharu, Lindqvist, Arne, Brink, Maartje C., Dantuma, Nico P., Katou, Yuki, Shirahige, Katsuhiko, Sjögren, Camilla
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4199498/
https://ncbi.nlm.nih.gov/pubmed/25329383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004680
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