The Chromosomal Association of the Smc5/6 Complex Depends on Cohesion and Predicts the Level of Sister Chromatid Entanglement

The cohesin complex, which is essential for sister chromatid cohesion and chromosome segregation, also inhibits resolution of sister chromatid intertwinings (SCIs) by the topoisomerase Top2. The cohesin-related Smc5/6 complex (Smc5/6) instead accumulates on chromosomes after Top2 inactivation, known...

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Auteurs principaux: Jeppsson, Kristian, Carlborg, Kristian K., Nakato, Ryuichiro, Berta, Davide G., Lilienthal, Ingrid, Kanno, Takaharu, Lindqvist, Arne, Brink, Maartje C., Dantuma, Nico P., Katou, Yuki, Shirahige, Katsuhiko, Sjögren, Camilla
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2014
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Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4199498/
https://ncbi.nlm.nih.gov/pubmed/25329383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004680
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