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Roles of Vertebrate Smc5 in Sister Chromatid Cohesion and Homologous Recombinational Repair

The structural maintenance of chromosomes (Smc) family members Smc5 and Smc6 are both essential in budding and fission yeasts. Yeast smc5/6 mutants are hypersensitive to DNA damage, and Smc5/6 is recruited to HO-induced double-strand breaks (DSBs), facilitating intersister chromatid recombinational...

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Bibliographische Detailangaben
Hauptverfasser: Stephan, Anna K., Kliszczak, Maciej, Dodson, Helen, Cooley, Carol, Morrison, Ciaran G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2011
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3135288/
https://ncbi.nlm.nih.gov/pubmed/21245390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00786-10
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