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Roles of Vertebrate Smc5 in Sister Chromatid Cohesion and Homologous Recombinational Repair

The structural maintenance of chromosomes (Smc) family members Smc5 and Smc6 are both essential in budding and fission yeasts. Yeast smc5/6 mutants are hypersensitive to DNA damage, and Smc5/6 is recruited to HO-induced double-strand breaks (DSBs), facilitating intersister chromatid recombinational...

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Detalhes bibliográficos
Main Authors: Stephan, Anna K., Kliszczak, Maciej, Dodson, Helen, Cooley, Carol, Morrison, Ciaran G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3135288/
https://ncbi.nlm.nih.gov/pubmed/21245390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00786-10
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