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Dichotomous mechanistic behavior in Narasaka–Heck cyclizations: electron rich Pd-catalysts generate iminyl radicals

Pd-catalyzed cyclizations of oxime esters with pendant alkenes are subject to an unusual ligand controlled mechanistic divergence. Pd-systems modified with electron deficient phosphines (e.g. P(3,5-(CF(3))(2)C(6)H(3))(3)) promote efficient aza-Heck cyclization, wherein C–N bond formation occurs via...

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Bibliografiske detaljer
Udgivet i:Chem Sci
Main Authors: Race, Nicholas J., Faulkner, Adele, Shaw, Megan H., Bower, John F.
Format: Artigo
Sprog:Inglês
Udgivet: Royal Society of Chemistry 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5963672/
https://ncbi.nlm.nih.gov/pubmed/29899895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5sc04037j
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