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Hes1 inhibitor isolated by target protein oriented natural products isolation (TPO-NAPI) of differentiation activators of neural stem cells

The Hes1 dimer inhibitor, agalloside (2), which can accelerate the differentiation of neural stem cells is described. Six natural products, including one new natural product, which bind to Hes1 were rapidly isolated by a developed “target protein oriented natural products isolation” (TPO-NAPI) metho...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Chem Sci
Egile Nagusiak: Arai, Midori A., Ishikawa, Naoki, Tanaka, Mitsuha, Uemura, Kenji, Sugimitsu, Noriko, Suganami, Akiko, Tamura, Yutaka, Koyano, Takashi, Kowithayakorn, Thaworn, Ishibashi, Masami
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Royal Society of Chemistry 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5963671/
https://ncbi.nlm.nih.gov/pubmed/29899896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5sc03540f
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