HS3ST2 expression is critical for the abnormal phosphorylation of tau in Alzheimer’s disease-related tau pathology

Heparan sulphate (glucosamine) 3-O-sulphotransferase 2 (HS3ST2, also known as 3OST2) is an enzyme predominantly expressed in neurons wherein it generates rare 3-O-sulphated domains of unknown functions in heparan sulphates. In Alzheimer’s disease, heparan sulphates accumulate at the intracellular le...

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Detalhes bibliográficos
Publicado no:Brain
Main Authors: Sepulveda-Diaz, Julia Elisa, Alavi Naini, Seyedeh Maryam, Huynh, Minh Bao, Ouidja, Mohand Ouidir, Yanicostas, Constantin, Chantepie, Sandrine, Villares, Joao, Lamari, Foudil, Jospin, Estelle, van Kuppevelt, Toin H., Mensah-Nyagan, Ayikoe Guy, Raisman-Vozari, Rita, Soussi-Yanicostas, Nadia, Papy-Garcia, Dulce
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5963411/
https://ncbi.nlm.nih.gov/pubmed/25842390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awv056
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