Rho-Kinase Inhibition Ameliorates Dasatinib-Induced Endothelial Dysfunction and Pulmonary Hypertension

The multi-kinase inhibitor dasatinib is used for treatment of imatinib-resistant chronic myeloid leukemia, but is prone to induce microvascular dysfunction. In lung this can manifest as capillary leakage with pleural effusion, pulmonary edema or even pulmonary arterial hypertension. To understand ho...

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Detaylı Bibliyografya
Yayımlandı:Front Physiol
Asıl Yazarlar: Fazakas, Csilla, Nagaraj, Chandran, Zabini, Diana, Végh, Attila G., Marsh, Leigh M., Wilhelm, Imola, Krizbai, István A., Olschewski, Horst, Olschewski, Andrea, Bálint, Zoltán
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2018
Konular:
Physiology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5962749/
https://ncbi.nlm.nih.gov/pubmed/29867576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2018.00537
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