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Low affinity TCRs support regulatory T cell function in autoimmunity
Regulatory T cells utilize a distinct TCR repertoire and are more self-reactive compared to conventional T cells. However, the extent to which TCR affinity regulates the function of self-reactive Tregs is largely unknown. In this study, we utilized a two-TCR model to assess the role of TCR affinity...
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| Pubblicato in: | J Immunol |
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| Autori principali: | , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5962277/ https://ncbi.nlm.nih.gov/pubmed/29282307 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1700156 |
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