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Polypharmacology Within the Full Kinome: a Machine Learning Approach

Protein kinases generate nearly a thousand different protein products and regulate the majority of cellular pathways and signal transduction. It is therefore not surprising that the deregulation of kinases has been implicated in many disease states. In fact, kinase inhibitors are the largest class o...

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שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:AMIA Jt Summits Transl Sci Proc
Main Authors: Jones, Derek, Bopaiah, Jeevith, Alghamedy, Fatemah, Jacobs, Nathan, Weiss, Heidi L., de Jong, W.A., Ellingson, Sally R.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Medical Informatics Association 2018
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5961802/
https://ncbi.nlm.nih.gov/pubmed/29888050
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