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Fluorescence Spectroscopy Reveals N-terminal Order in Fibrillar Forms of α-Synuclein

The neuronal protein α-synuclein (αS) plays a key role in Parkinson’s Disease, forming inclusions termed Lewy Bodies and Lewy Neurites. Recent improvements in cryo-electron diffraction and solid state NMR (ssNMR) have led to the elucidation of the structures of peptides derived from the αS fibril co...

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Bibliografiske detaljer
Udgivet i:Chem Commun (Camb)
Main Authors: Haney, Conor M., Petersson, E. James
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5961496/
https://ncbi.nlm.nih.gov/pubmed/29313531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7cc08601f
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