PRMT5 as a druggable target for glioblastoma therapy

BACKGROUND: In spite of standard multimodal therapy consisting of surgical resection followed by radiation and concurrent chemotherapy, prognosis for glioblastoma (GBM) patients remains poor. The identification of both differentiated and undifferentiated “stem cell like” populations in the tumor hig...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Banasavadi-Siddegowda, Yeshavanth Kumar, Welker, Alessandra M, An, Min, Yang, Xiaozhi, Zhou, Wei, Shi, Guqin, Imitola, Jaime, Li, Chenglong, Hsu, Sigmund, Wang, Jiang, Phelps, Mitch, Zhang, Jianying, Beattie, Christine E, Baiocchi, Robert, Kaur, Balveen
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Basic and Translational Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5961180/
https://ncbi.nlm.nih.gov/pubmed/29106602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox206
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