PRMT5–PTEN molecular pathway regulates senescence and self-renewal of primary glioblastoma neurosphere cells

Glioblastoma (GBM) represents the most common and aggressive histologic subtype among malignant astrocytoma and is associated with poor outcomes because of heterogeneous tumour cell population including mature non-stem-like cell and immature stem-like cells within the tumour. Thus, it is critical to...

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Bibliographic Details
Published in:Oncogene
Main Authors: Banasavadi-Siddegowda, YK, Russell, L, Frair, E, Karkhanis, VA, Relation, T, Yoo, JY, Zhang, J, Sif, S, Imitola, J, Baiocchi, R, Kaur, B
Format: Artigo
Language:Inglês
Published: 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5240810/
https://ncbi.nlm.nih.gov/pubmed/27292259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2016.199
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