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Debate: The slippery slope of surrogate outcomes

Surrogate outcomes are frequently used in cardiovascular disease research. A concern is that changes in surrogate markers may not reflect changes in disease outcomes. Two recent clinical trials (Heart and Estrogen/Progestin Replacement Study [HERS], and the Antihypertensive and Lipid-Lowering Treatm...

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Bibliografische gegevens
Gepubliceerd in:Curr Control Trials Cardiovasc Med
Hoofdauteur: D'Agostino, Ralph B
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BMC 2000
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC59603/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11714414/
https://ncbi.nlm.nih.govhttps://doi.org/10.1186/cvm-1-2-076
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