Two Decades of Cardiovascular Trials With Primary Surrogate Endpoints: 1990–2011

Background Surrogate endpoint trials test strategies more efficiently but are accompanied by uncertainty about the relationship between changes in surrogate markers and clinical outcomes. Methods and Results We identified cardiovascular trials with primary surrogate endpoints published in the New En...

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Hlavní autoři:	Behnood Bikdeli, Natdanai Punnanithinont, Yasir Akram, Ike Lee, Nihar R. Desai, Joseph S. Ross, Harlan M. Krumholz
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Wiley 2017-03-01
Edice:	Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Témata:	clinical trial outcome surrogate endpoints
On-line přístup:	https://www.ahajournals.org/doi/10.1161/JAHA.116.005285
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