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Debate: The slippery slope of surrogate outcomes

Surrogate outcomes are frequently used in cardiovascular disease research. A concern is that changes in surrogate markers may not reflect changes in disease outcomes. Two recent clinical trials (Heart and Estrogen/Progestin Replacement Study [HERS], and the Antihypertensive and Lipid-Lowering Treatm...

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Hlavní autor: D'Agostino, Ralph B
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2000
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC59603/
https://ncbi.nlm.nih.gov/pubmed/11714414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cvm-1-2-076
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