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Debate: The slippery slope of surrogate outcomes
Surrogate outcomes are frequently used in cardiovascular disease research. A concern is that changes in surrogate markers may not reflect changes in disease outcomes. Two recent clinical trials (Heart and Estrogen/Progestin Replacement Study [HERS], and the Antihypertensive and Lipid-Lowering Treatm...
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2000
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC59603/ https://ncbi.nlm.nih.gov/pubmed/11714414 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cvm-1-2-076 |
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