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Distinct gating mechanism of SOC channel involving STIM–Orai coupling and an intramolecular interaction of Orai in Caenorhabditis elegans
Store-operated calcium entry (SOCE), an important mechanism of Ca(2+) signaling in a wide range of cell types, is mediated by stromal interaction molecule (STIM), which senses the depletion of endoplasmic reticulum Ca(2+) stores and binds and activates Orai channels in the plasma membrane. This insi...
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| Izdano u: | Proc Natl Acad Sci U S A |
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| Glavni autori: | , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
2018
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5960282/ https://ncbi.nlm.nih.gov/pubmed/29712850 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1714986115 |
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