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An Endoplasmic Reticulum/Plasma Membrane Junction: STIM1/Orai1/TRPCs

Ca2+ entering cells through store-operated channels (SOCs) affects most cell functions, and excess SOC is associated with pathologies. The molecular makeup of SOCs and their mechanisms of gating were clarified with the discovery of the Orais and STIM1. Another form of SOCs are the TRPCs. STIM1 gates...

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Detalhes bibliográficos
Main Authors: Lee, Kyu pil, Yuan, Joseph P., Hong, Jeong Hee, Worley, Paul F., Muallem, Shmuel
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2866752/
https://ncbi.nlm.nih.gov/pubmed/19944100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2009.11.078
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